How Psilocybin Can Rewire Our Brain, Its Therapeutic Benefits & Its Risks
Huberman Lab

How Psilocybin Can Rewire Our Brain, Its Therapeutic Benefits & Its Risks

podcasts

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The Effects of Psilocybin on Serotonin Levels

Key takeaways:

  • Standard antidepressants involve serotonin being sprayed at different locations in the brain, while psilocybin selectively and strongly binds to and activates the serotonin-2a receptor. Serotonin-2a receptors are located in the neocortex, including the prefrontal cortex which is involved in understanding context and switching categories.